Oral Progestagen for Management of Aspects of Breeding in Mares and Fillies.

Composition
Contains: Altrenogest 2.2 mg/mL in a medium chain triglyceride solution.

Features and Benefits
Altrenogest induces a hormonal state resembling pregnancy by mimicking the action of endogenous progesterone. Treatment with altrenogest blocks follicle development and oestrus in non-pregnant animals by suppressing cyclical release of gonadotrophins. Pituitary inhibition rapidly declines upon cessation of treatment and follicle development and ovulation rapidly returns. In pregnant animals, altrenogest supplements the natural progesterone levels. Treatment with altrenogest assists regulation and management of the breeding cycle and pregnancy in mares and fillies.

Indications
1. For regulation and control of the breeding cycle of mares:
a) To induce ovulatory oestrus early in the breeding season in mares where some follicular activity exists;
b) For the suppression of oestrus either during prolonged oestrus or in normally cycling mares;
c) For the control of the ovarian cycle in breeding mares to allow the most efficient use of the stallion.
2. For the maintenance of pregnancy in habitually aborting mares, or mares at risk of early embryonic death or abortion, where progesterone deficiency is thought to be the underlying cause.

Dosage and Administration
Administer 1 mL per 50 kg bodyweight (0.044 mg/kg altrenogest) daily. [For a 500 kg horse, 10 mL provdies 22 mg altrenogest.] 1. For regulation and control of the breeding cycle of mares
a) To induce ovulatory oestrus or to induce cyclical ovarian activity in mares with some follicular activity early in the breeding season; administer daily for 10 consecutive days;
b) To suppress oestrus in normally cycling mares; administer daily for 15 consecutive days.
To suppress prolonged oestrus; administer daily for 10 consecutive days.
c) To control the breeding cycle of mares to allow the most efficient use of the stallion; administer daily for 15 consecutive days.
2. For the maintenance of pregnancy in habitually aborting mares, or mares at risk of early embryonic death or abortion; administer daily from the 2nd or 3rd day after ovulation in the mated or inseminated mare, continuing daily until day 120 of gestation.

Presentation
1 Litre HDPE container with separate pump-top dispenser.

Storage
Store below 25C (Air Conditioning). Protect from light. Replace lid tightly after use. Store container in an upright position at all times.

Poisons Schedule


APVMA Approval Number


General Notes
Ultrasound scanning to confirm pregnancy is recommended on day 14 or 15 after ovulation. If the mare is not pregnant, cease READYSERVE administration and administer an injection of prostaglandin F2α to destroy any remnant luteal tissue, allowing the mare to return to oestrus and be re-mated.

CONTRAINDICATIONS: Not for use in stallions or geldings. Contraindicated for use in mares with uterine infections.
Feed must be destroyed and not given to any other animal. Product must be added to the feed immediately prior to consumption and feed is not to be stored.
Meat Withholding Period: NOT TO BE USED less than 28 DAYS before slaughter for human consumption.
Competition withholding period: The regulations of local racing or competition authorities in your country should be observed.

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