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Combined supplements of folic acid and Vitamin B12.
Composition
FOLIC ACID/B12 INJECTION:
Folic acid 15 mg/mL
Cyanocobalamin (Vit B 12) 500 ug/mL
Features and Benefits
FOLIC ACID & VITAMIN B12 are essential B Complex vitamins, both vitally
involved in many critical metabolic processes related to coenzymes for tissue
formation, DNA synthesis, complete utilisation of carbohydrates and proteins for nervous tissue maintenance and energy production, and blood counts.
FOLIC ACID and VITAMIN B12 act in synergy in the formation of DNA , and
deficiencies can have serious consequences, both in performance horses with a high tissue turnover rate, and in pregnancy and growth of young foals.
Clinically the first sign of deficiency is anaemia. Lack of either FOLIC ACID or VITAMIN B12 can create anaemias. As the deficiency may be indistinguishable
for either of these essential vitamins, they are often grouped in one product for therapeutic and preventive use.
Indications
FOLIC ACID is an essential B Group vitamin which is involved in many metabolic processes as an important coenzyme. Its most important role is in the formation of nucleic acids (DNA) from amino acids.
FOLIC ACID (along with VITAMIN B12, Vitamin B6, Vitamin C and Iron) is vital to the formation of red and white blood cells and haemoglobin, as well as for rapidly dividing cells which include gastrointestinal epitheleal cells, the growing foetus, skin and hair.
FOLIC ACID is involved in the formation of the amino acids methionine and
glycine, as well as the vitamin choline. Vitamin B12 is essential to the
formation of FOLIC ACID. Folate is abundant in fresh, green feeds, but
processing feed rapidly destroys it. FOLIC ACID supplementation is highly
recommended during pregnancy, as deficiencies in young growing animals are often associated with retardation.
Cooking and storage of feeds destroy Folic Acid levels.
When antibiotics, particularly Sulphur drugs, are used for extended periods, the normal synthesis of Folic acid in the gut will be reduced, and the requirement for Folic Acid are increased.
FOLIC ACID requirements are far greater in athletic performance horses where the synthesis and absorption from the gut are reduced by the stress of training and performance.
Supplements of FOLIC ACID are reported to improve antibody response in
animals.
VITAMIN B12 is useful to stimulate appetite in horses, and is essential in
maintenance of adequate blood counts.
Dosage and Administration
Give 5 - 10 mL by intramuscular injection regularly twice weekly, or as advised by a veterinary surgeon.
FOLIC ACID/ VITAMIN B12 can be used with all Nature Vet products.
Presentation
100 mL sterile injection, as FOLIC ACID/VITAMIN B12 100 mL
Storage
Store below 25o C (air conditioning). Protect from light (always store in box).
Poisons Schedule
APVMA Approval Number
51116
General Notes
Trainers Tips:
Pregnancy:
FOLIC ACID is critically involved with
VITAMIN B12, VITAMIN C and Cobalt
metabolism.
FOLIC ACID should be supplemented in
brood mares during pregnancy, and in
young, growing foals.
Performance:
FOLIC ACID is vital in the reformation of
high turnover cells, and in stressed
performance horses the synthesis of
FOLIC ACID in the gut, and absorption
from the gut, may be inadequate. Also
consider supplementation whenever
sulphur-based antibiotics have been used.
B Complex Vitamins:
Are water soluble, and required in regular
amounts at all times. FOLIC ACID and
VITAMIN B12 are members of this group
of vitamins, which are essential to a wide
range of body processes.
As the anaemias caused by deficiency of
either FOLIC ACID or VITAMIN B12 are
clinically indistinguishable, the two
vitamins are effectively combined in the
one product.
Other Nature Vet preparations contain
Vitamin B12, and may be more appropriate
to certain requirements. Consider VAM,
VITAMIN B COMPLEX or COPHOS B.
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